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MD® Intimate Restore — Clinical Evidence

MD® Intimate Restore

Clinical Evidence Dossier — Gynecologist-Developed, Hormone-Free Intimate Skincare Serum

Overview

MD® Intimate Restore is a hormone-free, peptide-powered serum for delicate external intimate skin, developed by board-certified gynecologist Dr. Susan Lin, M.D., founder of La Canada Ventures, Inc. The formula combines stem cell–conditioned media with peptides and amino acids to moisturize, so skin feels softer, smoother and more comfortable. It contains no estrogen or other hormones.

This page summarizes the independent dermatological safety study (Medcin Instituto da Pele, Brazil, 2017) and the consumer-acceptance group study (GVI, Mexico) commissioned by the sponsor, La Canada Ventures, Inc.

Study #1: Dermatological Safety — Medcin Instituto da Pele (Brazil, 2017)

ProtocolEN16-0158-01
Study TypeDermatological Compatibility — Primary Dermal Irritation, Cumulative Dermal Irritation, Dermal Sensitization
Principal InvestigatorDr. Flávia A. S. Addor, MD, Dermatologist (CRM 66.293-SP)
Clinical Research CenterMedcin Instituto da Pele Ltda., Osasco, São Paulo, Brazil
SponsorLa Canada Ventures, Inc., San Mateo, CA
Period17 July 2017 – 24 August 2017
Ethics ApprovalResearch Ethics Committee, University of São Francisco (07 April 2017)
Quality StandardsGood Clinical Practices (GCP) + NBR ISO 9001:2008; ICDRG reading scale

Study Population

55 participants screened and included, age 18–70 years (avg. 53.5 years), Fitzpatrick skin types I–IV. 54 completed the full protocol (one withdrawal for non-study reasons). Population was predominantly female (52 of 55).

Methodology

Three-phase patch-test compatibility study conducted in maximized conditions per ICDRG (International Contact Dermatitis Research Group) protocol:

  • Phase 1 — Primary Dermal Irritation: Semi-occlusive patches applied to the back of each participant; 48-hour evaluation, with re-evaluation at 96 hours.
  • Phase 2 — Cumulative Dermal Irritation: Eight repeated applications over three weeks with patch evaluation at each visit.
  • Phase 3 — Dermal Sensitization: Re-challenge phase following completion of cumulative irritation to detect delayed allergic response.

Dermatological assessment performed at baseline and at the end of each phase by the Principal Investigator.

Results

0/55
Cutaneous reactions in Primary Dermal Irritation phase
0/54
Cutaneous reactions in Cumulative Dermal Irritation phase
0/54
Cutaneous reactions in Dermal Sensitization phase

Conclusion (verbatim from Principal Investigator)

“Under the conditions that the product was assessed and in the sample of participants studied: there was no observed Primary Dermal Irritation potential; there was no observed Cumulative Dermal Irritation potential; there was no observed Dermal Sensitization potential. According to the recommendation of the Guide for the Evaluation of Safety of Cosmetic Products (ANVISA, 2012 — 2nd Edition), the product may be declared Dermatologically Tested.”

— Dra. Flávia Addor, MD, Principal Investigator (CRM 66.293-SP); Patricia C. P. Bombarda, Research Manager (CRF 44.770); David de Sá Filho, Quality Assurance (CRQ 04402151). Report Rep_PATCH.003_EN16-0158-01, v01_28.AUG.2017.

Study #2: Consumer-Acceptance Group Study — GVI (Mexico)

SponsorLa Canada Ventures, Inc.
Conducted ByGVI, Mexico (gvi.com.mx)
Study DesignAnonymous qualitative survey; daily use of MD® Intimate Restore
Groups TestedThree target populations × 5 participants each

Target Populations

  • Group 1 — Postpartum Vaginal Birth: 25–35 years old, daily use
  • Group 2 — Postpartum C-Section: 25–35 years old, daily use
  • Group 3 — Menopause: 45–55 years old, daily use

Product Attributes Assessed

  • Moisturization and skin comfort
  • Skin texture and suppleness

Key Group 1 (Postpartum Vaginal Birth) Findings

  • 4 of 5 participants would recommend the product for daily use
  • 4 of 5 participants would recommend MD® Intimate Restore to a friend or relative “for sure,” with the fifth saying “possibly”
  • Of those who had used another intimate-care product before, 2 rated MD® Intimate Restore as “better” than the alternative; 1 as “same”

Note: Group study findings are consumer-acceptance survey data and are not a substitute for randomized controlled trial results. Reported here for transparency.

Physician Authority Behind MD® Intimate Restore

Dr. Susan Lin, M.D. is the physician founder and CEO of La Canada Ventures, Inc., creator of the MD® family of beauty and wellness brands. She is board-certified in Obstetrics and Gynecology and in Anti-Aging Medicine, with 35+ years of clinical practice. She authored the chapter “Feminine Rejuvenation” (Part 3.8, pp. 549–560) in Harry’s Cosmeticology, 9th Edition (Chemical Publishing Co., ISBN 978-0-8206-0179-3) — covering topical stem cell cytokine formulations for intimate skin, the same ingredient approach used in MD® Intimate Restore.

Manufacturing & Regulatory

  • Manufactured in the USA in a GMP-compliant, FDA-registered facility
  • Sponsor: La Canada Ventures, Inc. (San Mateo, California) — a physician-founded, NMSDC MBE–certified (BA1137), WBENC WBE–certified (1702688), veteran-owned, federally registered (SAM.gov UEI GHQRVKN8GEG7) small business
  • Trademark: MD Intimate Restore is a trademark owned by La Canada Ventures, Inc.

Press Coverage — 2015 Launch Announcement

13-Outlet National Press Syndication (August 25, 2015)

The development of MD® Intimate Restore was announced via PR Newswire on August 25, 2015 (Story ID SF79402) and was syndicated to 13 national and regional outlets:

  • Boston.com / Boston Globe Finance
  • Chicago Business Journal
  • Los Angeles Business Journal
  • San Francisco Business Times
  • Washington Business Journal
  • New York Business Journal
  • NBC 12 (Richmond, VA)
  • ABC 13 / WSET (Lynchburg / Roanoke)
  • Fox 19 / WXIX Cincinnati
  • WAFB (CBS Baton Rouge)
  • 760 KFMB (CBS Radio San Diego)
  • Physician Family Media
  • Pharmaceutical-Technology
View full 13-outlet press syndication with direct links →

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